BizUnit Designer
From CodePlex:
BizUnit Designer is a GUI that allows rapid creation of BizUnit test cases which can be used for unit testing or system testing distributed applications. The easy to use drag and drop user interface has minimal learning curve which will get you up and running with test cases in a matter of minutes.
I’ve used BizUnit on a couple of projects (even non-BizTalk projects) and I think it’s very useful.